On Brauner and Soru's reaction to tbc with "blue" sticks

Abstract

In 1931, Brauner and Soru performed a series of experiments to clarify the relationship between the red blood cells of normal and immunized animals with the corresponding microbes. For this purpose, they took the red blood cells of healthy rabbits and mixed them with bacilli of typhoid, intestinal and b. tumefaciens. Having then prepared smears from each mixture and stained them, they examined them under a microscope, and the picture in all cases was the same: microbes in large and small clumps were located between the red blood cells and only a few microbes were adsorbed red blood cells. Completely different results were obtained with blood of immunized animals; if we take erythrocytes of a rabbit immunized against b. coli and mix them with these microbes, in smears it appears that most microbes are adsorbed by erythrocytes (sometimes 2-3 concentrated series) and only a small number are located freely.