Abstract
Aim. To determine the age peculiarities of infectious mononucleosis (IM), caused by Epstein-Barr virus, in hospitalized children. Materials and methods. On the basis of case histories of 50 children with infectious mononucleosis, caused by Epstein-Barr virus, who were hospitalized to children’s unit of Perm Regional Clinical Infectious Hospital in 2015, retrospective clinicostatistical analysis was carried out. Results. By means of mathematical prognostic modeling of age peculiarities of infectious mononucleosis, induced by Epstein-Barr virus, direct correlation dependence between children’ age and development of hepatitis with cytolysis syndrome was stated. To assess the probability of risk, a logistic classification model was developed. It was indicated that children over 3, despite moderately severe disease, are usually hospitalized reliably later, than younger children that can have unfavorable consequences due to late therapy of hepatitis. Conclusions. The created logistic classification model for assessment of age-dependent probability of risk for the development of hepatitis with cytolysis syndrome in Epstein-Barr infection indicated its growth by 1.5 times in children, reaching the age of 5.5 years.
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