Abstract

The SARS-CoV-2 virus which causes the disease termed COVID-19 ripped through the globe in the latter part of 2019 and has left a state of fear, death and destruction in its wake. The Omicron variant was officially announced by the South African authorities on the 24th of November 2021, with the first confirmed sample of the infection being collected on the 9th of November 2021. The initial cases were flagged as a possible new variant due to the stark differences in the presentation and clinical features of the patients. At the time of Omicron’s discovery, the predominant variant circulating within South Africa was the Delta variant B.1.617.2 which typically presented with more severe and distinct symptoms.Omicron spread rapidly within the Southern Africa and abroad, principally South Africa, Botswana, Hongkong and Israel were among the first countries to record cases of the new variant. The first European case of the Omicron variant was confirmed on the 26th of November 2021 in Belgium. Towards the end of November 2021 cases of the new variant had been confirmed and recorded in France, the United Kingdom, Germany, Portugal and Scotland. Additional cases of the Omicron variant have been confirmed in Canada, Australia, India and United States.At this current point in the development of the Omicron upsurge in cases the international community should aim for further vaccinations among their fellow countrymen, but more so vaccine equality should be ensured. Such equality should be ensured in the developing nations as the virus does not respect any boundaries or territories and thus a higher level of vaccination worldwide will confer greater protection to the global community as a whole.

Highlights

  • The SARS-CoV-2 virus, which causes the disease termed COVID-19 ripped through the globe in the latter part of 2019 and has left a state of fear, death and destruction in its wake

  • The lack of international and global partnership as well as skepticism surrounding the vaccine efficacy set the stage for the development and discovery of the new variant, namely (B.1.1.529) / 21K(Omicron) which very harshly exposed the fragile and false veil of protection that the world has been living under, with weakened and eased health protocols and softer mask mandates. [1,2] The discovery The Omicron variant was officially announced by the South African authorities on the 24th of November 2021, with the first confirmed sample of the infection being collected on the 9th of November 2021

  • The initial findings of the mutations present in Omicron called for the WHO to label the variant as one of “concern”, due to it having more mutations than the Delta variant which is still causing thousands of deaths internationally. [3,4,5] The mutations The greatest concern caused by the newly discovered Omicron variant is the myriad of mutations it possesses.The omicron variant is shown to have over 50 mutations with more than 30 of them explicitly being in the spike protein of the virus

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Summary

Introduction

The SARS-CoV-2 virus, which causes the disease termed COVID-19 ripped through the globe in the latter part of 2019 and has left a state of fear, death and destruction in its wake. The lack of international and global partnership as well as skepticism surrounding the vaccine efficacy set the stage for the development and discovery of the new variant, namely (B.1.1.529) / 21K(Omicron) which very harshly exposed the fragile and false veil of protection that the world has been living under, with weakened and eased health protocols and softer mask mandates.

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