Abstract
To report a distinct optical coherence tomography (OCT) appearance of macular combined hamartoma of retina and retinal pigment epithelium (CHRRPE). This is a retrospective case series of four eyes of four patients with macular CHRRPE who were assessed with the help of color fundus photographs, swept-source OCT (SS-OCT), and fundus fluorescein angiography wherever required. All four patients presented with decreased visual acuity. SS-OCT in all patients showed adherent epiretinal membrane (ERM) and localized thickening of underlying retina. An omega-shaped disorganization of inner retinal layers was seen bounded posteriorly by the outer plexiform layer. This was termed, "Omega sign." Omega sign is a characteristic feature of macular CHRRPE and may help to distinguish macular CHRRPEs from ERMs. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:122-125.].
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