Abstract
Omalizumab is a recombinant humanized monoclonal antibody against IgE, which can lower the level of free IgE in plasma and inhibit a series of biological effects caused by IgE by selectively binding to high-affinity IgE receptors. At the same time, it can regulate the behavior of basophilic granulocytes, mast cells and B cells. Clinically, it is mainly used in the treatment of asthma, urticaria, eczema and other allergic diseases, and has shown a favorable safety and tolerability profile. It is expected to bring new hope for the treatment of allergic diseases. Key words: Hypersensitivity; Antibodies,monoclonal; Immunoglobulin E; Immunotherapy
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