Abstract
The discovery of an acid labile metabolite of olsalazine, tentatively identified as olsalazine-O-sulphate, is described. Due to its acid labile properties, this conjugate was previously co-determined with olsalazine. Based on this finding, a new assay has been developed making it possible to determine both olsalazine and olsalazine-O-sulphate simultaneously. The initial aim of this study was to simplify an original analytical method in order to improve sample throughput without loss of sensitivity. However, during this work, a previously unidentified acid labile metabolite was discovered. The characterization of this metabolite is described here.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Scandinavian journal of gastroenterology. Supplement
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
