Abstract

Lipopolysaccharides isolated from Fusobacterium nucleatum (F. nucleatum) strain Fl was split by hydrolysis with 1% acetic acid into water‐soluble polysaccharide and insoluble material. Gel filtration of the water‐soluble polysaccharide on Bio‐Gel P‐60 gave a serologically active fraction eluted at the void volume (Vo) of the column with a sugar composition similar to that of the parent LPS and a fraction eluted at 2.5 × Vo. The latter, supposed to represent the core polysaccharide, contained phosphorus, glucosamine, L‐ and D‐glycero‐D‐manno‐heptose, galactose, glucose, and 2‐keto‐3‐deoxyoctonate.

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