Abstract
Electrophysiological recordings demonstrated strong olfactory receptor responses to intravascularly injected odorants in tracheotomized animals. This disproves the belief that such odorants reach olfactory receptors only via exhaled air and strongly suggests that blood-borne odorants can stimulate receptors by diffusing from nasal capillaries. Blood-borne odorants originating physiologically and pathologically may similarly stimulate receptors, thereby modifying olfactory function.
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