Abstract

The article describes a classical case of olfactory neuroblastoma in a 33-year-old female patient diagnosed with
 «nasal cavity neoplasm (polyp?)» who was referred to the National Centre for Neurosurgery JSC from the ENT Department
 of the City Hospital No. 1. The first symptoms of the tumor occurred during her pregnancy. The aggressive tumor has invaded the anterior cranial fossa and spread into the right half of
 the ethmoid sinuses and the orbit. The tumor diagnostics was
 complicated by the prevalence of symptoms of a nasal cavity
 neoplasm. The “olfactory neuroblastoma” diagnosis was verified by clinical observations, MRI, and pathomorphological
 studies. Histological examination of the tumor showed a typical structure of olfactory neuroblastoma. IHC examination
 showed an expression of neuronal differentiation markers.
 The degree of malignancy was determined by Hyams grade

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