Abstract
The purpose of the study is to demonstrate the possibility and information content of olfactory bulb volume measuring in healthy volunteers and patients with deviated nasal septum, as well as the relationship between the volume of the olfactory bulb and olfactory function. Material and methods. 28 men with deviated nasal septum aged 24 to 35 years (main group) and 21 clinically healthy volunteers, men aged 23 to 33 years (control group) were examined. All patients underwent checkup of the ENT organs and examinations on a 1.5 T MRI machine with 12-channel head coil. The sense of smell was examined using the extended Sniffin Sticks test (SST) (“Buerhard”, Hamburg, Germany) with the definition of 3 parameters: threshold, identification and discrimination. Results. In accordance with the design of the work, threshold, discrimination, identification subtests and MRI examination of the head were performed with the measurement of the olfactory bulb volume of patients in the main group and volunteers in the control group. In all participants in the control group was diagnosed normosmia in accordance with the TDI indicator, and in patients with deviated nasal septum – hyposmia. Olfactory function in patients deviated nasal septum was significantly lower on the narrower side as indicated for odor thresholds, odor recognition, and odor identification (P<0.01). It was found that olfactory bulb volumes are larger on the wider side than on the narrower side (P<0.01). Conclusion. Asymmetry in the size and volume of OB is observed only in patients with deviated nasal septum, it is absent in healthy volunteers. MRI visualization and morphometry of olfactory bulb, in addition to identifying of the nasal cavity, paranasal sinuses state, are informative in the process of preoperative examination of patients with deviated nasal septum. Olfactory bulb volume definition should be used for personalized diagnosis and quantitative assessment of olfactory dysfunction.
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