Abstract
AbstractHyperbranched polysiloxane (HBPSi) as a novel unconventional fluorescent polymer has attached great attention due to its stable fluorescence, facile preparation, and good biocompatibility. Study shows that the fluorescence of unconventional fluorescent polymer is closely related to the aggregate state. To promote the aggregate of HBPSi and endow it with drug delivery ability, in this work, different contents of renewable oleic acid are grafted onto a water‐soluble HBPSi. Results show that oleic acid constructs compact supramolecular HBPSi, leading to the enhancement of electronic communication among hydroxyl, amine, ether, and ─Si(O)3 groups in the supramolecular, which inhibits the movement of molecular chains and subsequently enhances the fluorescence. The novel compact supramolecular HBPSi has a high drug loading capacity (470 mg g–1) due to its typical structure, which is much higher than the reported β‐cyclodextrin modified HBPSi (180 mg g–1), and the drug release is also pH‐controlled. Moreover, the fluorescence of HBPSi‐OA is sensitive to Fe3+. Therefore, the supramolecular HBPSi can be applied in drug delivery and Fe3+ sensing.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.