Abstract

Controversy exists regarding the management of blood pressure (BP) in older people for the prevention of cognitive impairment or dementia.1 Is it safe and effective to substantially lower BP in older patients or will there be untoward effects such as stroke and worsening of cognition, syncope, or other adverse events?1 On the basis of observational epidemiological studies, it has long been held that raised BP in midlife predicts cognitive impairment or dementia in later life. However, the association of elevated BP as a predictor of dementia is less clear in older people.

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