Abstract

Tomomi Itaya, Isato Tsuge, Toshio Kimura, Yasuhiro Ito, Masakazu Kouketsu and Syunkichi Baba (Nagoya City University Medical School)The relationship between the HLA type and disease has been reported by many authors. Watanabe (1983) reported that patients with HLA B5 (BW51, BW52) were considered to be highly responsive to OK-432.We used local injection of OK-432 in 4 cases of head and neck tumor, and investigated the relationship between their respose and the HLA type, clinically and histologically.Among our cases, we could not find any patients with HLA B5 highly responsive to OK-432. However, it is useful to know the responsiveness of OK-432 before treatment.

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