Abstract

According to the medical literature, both on-pump and off-pump coronary artery surgery is safe and effective in octogenarians. The aim of our study was to examine the epidemiology, in-hospital outcomes and long-term follow-up results in octogenarians undergoing off-pump and on-pump coronary artery surgery utilizing nationwide registry data. All octogenarians (≥ 80 years) enrolled in the Polish National Registry of Cardiac Surgical Procedures (KROK Registry), who underwent isolated coronary surgery between January 2006 and September 2017 were identified. Preoperative data, perioperative complications, hospital mortality and long-term mortality were analyzed. Unadjusted and propensity-matched comparisons were performed between octogenarians undergoing off-pump and on-pump coronary artery bypass surgery. Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing. Among 6,006 analyzed patients, 2,744 (45.7%) were operated on-pump and 3,262 (54.3%) were operated off-pump. Propensity-matched analysis revealed that patients operated on-pump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively). Long-term all-cause mortality was lower among patients operated off-pump (p = 0.013). On the basis of our findings we suggest that off pump technique should be considered as perfectly acceptable in octogenarians.

Highlights

  • In the industrialized world, the average life expectancy continues to increase

  • Octogenarians accounted for 4.1% of the total population undergoing coronary artery surgery in Poland during the analyzed period (n = 152,631) and this percentage is increasing

  • Propensity-matched analysis revealed that patients operated onpump were more often reoperated due to postoperative bleeding and their in-hospital mortality was higher (6.6% vs 4.5%, p = 0.006 and 8.7% vs 5.8%, p = 0.001, respectively)

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Summary

Introduction

Patients over 80 years old are more prone to increased postoperative morbidity and mortality, because of more frequent comorbid risk factors and frailty [2, 3]. This population requires special care, attention, and treatment. Off-pump coronary artery bypass (OPCAB) grafting gives the surgeon the opportunity to avoid the inherent risks associated with coronary artery bypass surgery (CABG) with cardiopulmonary bypass. These increased risks include hemodilution, global myocardial ischemia, nonpulsatile arterial flow, systemic inflammatory response, and atherosclerotic embolization from aortic manipulation [4].

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