Abstract
The name Paul Krugman may lead you to think of the celebrated economist who won a Nobel Prize in 2008 for his work on international trade. Or you may be reminded of the prolific New York Times columnist who regularly takes aim at the Republican Party. Economist or columnist, they are, of course, one and the same man. And if you read Krugman you will also know that he projects formidable confidence, even certainty, in his pronouncements. It was not always so. Once Krugman was simply a young academic trying to forge a reliable reputation, a man struggling to be heard by the popular mainstream of his discipline. 20 years ago, that Paul Krugman was less confident, more reflective, and, in many ways, a great deal more compelling. His subject back then was what counts as valid evidence. His meditations on what we know—or choose to know—are pertinent to all areas of inquiry today, including medicine.
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