Offbeat phenomenon in antrum of highmore – Inflammatory myofibroblastic tumor

Abstract

The Inflammatory Myofibroblastic Tumor (IMT) is a rare benign pathology of the head and neck region that tends to mimic a malignancy on account of its aggressive clinical and radiographic features. There are various descriptive terms for this lesion due to the uncertainty of the biologic nature of the lesion, namely: Fibrous Xanthoma, Plasma Cell Granuloma, Pesudosarcoma, Lymphoid Hamartoma, Myoxid Hamartoma, Inflammatory Pseudotumor and Benign Myofibroblastoma. Inflammatory Myofibroblastic Pseudotumor occurs throughout the body, most frequently in the peritoneal cavity, retroperitoneal space and lungs, among extra pulmonary lesions 15% accounts for the head and neck region. Most commonly, they are located in the region of the orbit. Inflammatory Myofibroblastic tumor presentation in maxillary sinus is rare and has an invasive potential. We have presented a case report of Inflammatory Myofibroblastic tumor of maxillary sinus, correlating Clinical, radiographic, and histopathologic along with immunohistochemical profile to arrive at a diagnosis, with special emphasis on the disputed nosology of this lesion and the latest therapeutic update.