Abstract
The negative component of the electroretinogram was recorded from the enucleated eyeball as well as from the isolated perfused retina of the rabbit. Mainly the participation of this component in the off-effect was studied. The experimental conditions were: room temperature (19–22°C) d.c. amplification, white diffuse light stimuli ( 1.10 −4 to 5.10 2 lm/m 2 retinal illumination, 1–60 sec duration). The on-effect consists of a quick and a slow negative phase. With stimuli of short duration (1 sec) the slow component continues its descendent course even after termination of the stimulus. An immediate off-effect is only produced by stimuli of several seconds duration. It manifests itself by an exponential return to the base line. Stimuli of high intensity slow down this return. In the isolated retina an additional quick deflection is superimposed on the steady return to the base line resulting in a double-peaked off-effect. The quick phases in on- and off-effect are not produced by identical processes. In the discussion similar results of former intra- and extra-cellular studies are mentioned.
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