Abstract
Harold Varmus has made pioneering contributions to our understanding of cancer as a genetic disease. The discovery of the cellular origin of retroviral oncogenes earned him and his long-term collaborator, Michael Bishop, the Lasker Prize for Basic Medical Sciences in 1982 and the Nobel Prize in Physiology and Medicine in 1989. Throughout his career, Varmus has held several leadership roles that shaped science policy in the US and worldwide, and he has been an outspoken advocate for open science. In this interview, he talks (among other things) about the factors that shaped his early career choices, the thrill of scientific discovery, and the importance of including diverse populations in genomic studies of cancer and other diseases.
Highlights
Harold Varmus is the Lewis Thomas University Professor and a research group leader at Weill Cornell Medicine and a Senior Associate Member of the New York Genome Center, where he is helping to coordinate Polyethnic 1000, an initiative to study cancer genomes in ethnically diverse patient populations
The discovery of the cellular origin of retroviral oncogenes earned him and his long-term collaborator, Michael Bishop, the Lasker Prize for Basic Medical Sciences in 1982 and the Nobel Prize in Physiology and Medicine in 1989. Throughout his career, Varmus has held several leadership roles that shaped science policy in the US and worldwide, and he has been an outspoken advocate for open science
He started down his research path in 1968 in Ira Pastan’s laboratory at the National Institutes of Health (NIH), where he investigated regulation of gene expression in bacteria
Summary
Harold Varmus is the Lewis Thomas University Professor and a research group leader at Weill Cornell Medicine and a Senior Associate Member of the New York Genome Center, where he is helping to coordinate Polyethnic 1000, an initiative to study cancer genomes in ethnically diverse patient populations. Harold Varmus has made pioneering contributions to our understanding of cancer as a genetic disease.
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