Abstract
ABSTRACTA clinical study of oestrus control in bitches with chlormadinone acetate (CMA) is reported. The commercial 1‐0 per cent crystalline suspension of CMA was injected subcutaneously at a dose of 3 mg/kg, or somewhat lower for the largest animals. Treatment was initiated always in anoestrus and was repeated twice annually for as long as requested. The longest, 9‐year, period of anoestrus was achieved by twenty repeated treatments. A total of 2,471 treatments were given to 568 bitches (an average of 4‐4 treatments per bitch) during a period of over 10 years, with an efficacy of 98 per cent. The incidence of false pregnancy, uterine inflammatory disorders and mammary nodules in the treated group were compared to those of an age‐related control group of 487 bitches that did not receive hormonal treatment. A lower incidence of false pregnancy and the two clinical entities was observed in the group of treated animals. It is concluded that CMA can be used safely and reliably for oestrus control in bitches and is therefore, an appropriate alternative for ovariohysterectomy.
Published Version
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