Abstract
ObjectivesA definite geographic variation has been observed in the frequency of odontogenic tumors and giant cell lesions of the jaws reported from different parts of the world. However, there are a few studies on these lesions, especially giant cell lesions, reported from India. Hence, this study was designed to provide a demographic data on the odontogenic tumors and giant cell lesions reported from our institute located in the city of Hyderabad. Hyderabad is the capital city of the southern state of Andhra Pradesh in India. A retrospective analysis of odontogenic tumors and giant cell lesions of jaws reported in our institute between the years 2000 and 2009 was done and this data was compared with previous reports from different parts of the world and India.MethodsBiopsies of the lesions received between the years 2000 and 2009 were reviewed and patient's history, clinical, radiological and histopathological characteristics were analyzed.ResultsA total of 77 biopsies were received during the nine year study period. These lesions were more frequently seen in the males, in a younger age group and showed a predilection for the mandible. Most of them presented as radiolucent, slow growing and painless lesions. Ameloblastomas (71.4%) constituted the majority of odontogenic tumors while central giant cell granulomas (7.8%) constituted the majority of giant cell lesions.ConclusionThese lesions showed a definite geographic variation with ameloblastomas being the most common odontogenic tumors and odontomas being relatively rarer lesions in our region.
Highlights
The oro-facial region including the jaw bones, maxilla and mandible, is a site for a multitude of neoplastic conditions [1].Odontogenic tumours are lesions derived from epithelial, ectomesenchymal and/or mesenchymal elements that are a part of the tooth forming apparatus
Records of a total of 77 patients who presented with jaw swellings between the years 2000 and 2009 were retrieved and the tumors were classified according to the World Health Organization 2005 classification of odontogenic tumors [2]
Based on Indian literature survey, to date, we are reporting for the first time a study of this nature as, it has been observed that only individual case studies have been reported in the Indian context
Summary
Odontogenic tumours are lesions derived from epithelial, ectomesenchymal and/or mesenchymal elements that are a part of the tooth forming apparatus The majority of these tumors occur intraosseously within the maxillofacial skeleton, while extraosseous odontogenic tumors occur nearly always in the tooth-bearing mucosa [2]. Due to their specific structure and location they have been identified and classified by pathologists into a separate group, differing in histogenesis, biology, clinical manifestations and radiological signs from other tumors developing in the oral cavity and facial bones [3]. Giant cell lesions of the jaws are benign, tumor-like lesions affecting the jaws and occurring in other bones and soft tissues.
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