Abstract
Odontogenic myxofibroma is a rare variant of myxoma that produces collagen fibers. A 24-year-old male patient reported pain for over 5 days. Extraoral examination showed facial asymmetry on the left side of normal coloration and firm consistency. On intraoral examination, an expansion of the alveolar ridge of the left maxilla was observed. X-ray revealed a radiolucent multilocular lesion with irregular margins surrounding the floor of the maxillary sinus. Computed tomography scan showed a well-defined hypodense area with displacement of the third molar. Incisional biopsy was performed, and the histopathologic analysis revealed loose connective tissue, myxomatous, spindle and ovoid cells, and richly collagenized areas, compatible with odontogenic myxofibroma. The treatment was marginal resection, and 18 months of follow-up showed no recurrence. More aggressive treatment of the odontogenic myxoma/myxofibroma in the maxilla may be preferred because the closeness to the maxillary sinus can be a critical factor in case of recurrence. Odontogenic myxofibroma is a rare variant of myxoma that produces collagen fibers. A 24-year-old male patient reported pain for over 5 days. Extraoral examination showed facial asymmetry on the left side of normal coloration and firm consistency. On intraoral examination, an expansion of the alveolar ridge of the left maxilla was observed. X-ray revealed a radiolucent multilocular lesion with irregular margins surrounding the floor of the maxillary sinus. Computed tomography scan showed a well-defined hypodense area with displacement of the third molar. Incisional biopsy was performed, and the histopathologic analysis revealed loose connective tissue, myxomatous, spindle and ovoid cells, and richly collagenized areas, compatible with odontogenic myxofibroma. The treatment was marginal resection, and 18 months of follow-up showed no recurrence. More aggressive treatment of the odontogenic myxoma/myxofibroma in the maxilla may be preferred because the closeness to the maxillary sinus can be a critical factor in case of recurrence.
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