Abstract

This paper represents a study of 35 cases of odontogenic keratocyst (OKC) diagnosed in a Malaysian population. The clinical, radiological and histopathological features, treatment modalities and recurrence of this lesion were analysed. There was a higher prevalence rate among Malaysian Chinese (51.42 percent), while the Malays and Indians accounted for 22.86 percent and 25.72 percent respectively. The male to female ratio was 16 : 19. Age at presentation ranged from nine to 71 year, with about 70percent occurring between ages ten to 39 years. A total of 40 cysts were analysed. Of these, 67.5 percent occurred in the mandible and 32.5 percent in the maxilla. About 88 percent of OKC presented as unilocular radiolucencies and 42.0 percent were associated with unerupted or impacted teeth.Histologically, the parakeratinized OKC was the predominant variant found (75.8 percent). The majority of cases were treated by enucleation (85 percent), and a recurrence rate of 20 percent was recorded.

Highlights

  • The odontogenic keratocyst (OKC) is an unusual odontogenic cyst because of its unique clinical behaviour and high incidence of recurrence

  • The present study will attempt to give an update and a more detailed study of the clinical, radiological, histopathological and treatment aspects of this lesion as it occurs in the Malaysian population

  • OKC is reported to be found more frequently in males than females [1,3,4,5,6,7].The present series shows a slight female preponderance with a female to male ratio of 1.2 : 1. It was generally accepted that OKC may occur over a wide age range with a peak incidence in the second and third decades

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Summary

Introduction

The odontogenic keratocyst (OKC) is an unusual odontogenic cyst because of its unique clinical behaviour and high incidence of recurrence. Provisional diagnoses: In 15 cases (42.8 percent), a provisional diagnosis of odontogenic keratocyst was made. Histological findings: Out of the 35 cases studied, there were two primary cysts without typical features of keratocysts (probably because of infection or inflammatory reaction).

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