Abstract

ODFM is a data management system that integrates comprehensive omics information for microorganisms associated with various fermented foods, additive ingredients, and seasonings (e.g. kimchi, Korean fermented vegetables, fermented seafood, solar salt, soybean paste, vinegar, beer, cheese, sake, and yogurt). The ODFM archives genome, metagenome, metataxonome, and (meta)transcriptome sequences of fermented food-associated bacteria, archaea, eukaryotic microorganisms, and viruses; 131 bacterial, 38 archaeal, and 28 eukaryotic genomes are now available to users. The ODFM provides both the Basic Local Alignment Search Tool search-based local alignment function as well as average nucleotide identity-based genetic relatedness measurement, enabling gene diversity and taxonomic analyses of an input query against the database. Genome sequences and annotation results of microorganisms are directly downloadable, and the microbial strains registered in the archive library will be available from our culture collection of fermented food-associated microorganisms. The ODFM is a comprehensive database that covers the genomes of an entire microbiome within a specific food ecosystem, providing basic information to evaluate microbial isolates as candidate fermentation starters for fermented food production.

Highlights

  • Advances in next-generation sequencing technology have led to the rapid expansion of microbial genome sequence data

  • The ODFM is a web-based application developed in compliance with the HyperText Markup Language (HTML) 5 web standards and, is supported by most web browsers

  • The program was designed based on the Representational State Transfer (REST) service architecture to support use on various devices, including desktop computers and mobile devices

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Summary

Introduction

Advances in next-generation sequencing technology have led to the rapid expansion of microbial genome sequence data. We have developed the Omics Database of Fermentative Microbes (ODFM), a data management system that integrates comprehensive omics information for fermentative microorganisms at the World Institute of Kimchi funded by the Korean government. The ODFM offers curated omics sequences of fermented food-associated bacteria, archaea, eukaryotic microorganisms, and viruses, and several analytical tools that enable gene diversity and taxonomic analyses of an input query on the database at the whole genome level.

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