Abstract

The first of the newer antibiotics to show a striking activity against Pasteurella tularensis was streptomycin, as reported by Heilman 1 in 1944. To the present time this drug has been the treatment of choice. Since the oculoglandular form of tularemia is the unusual manifestation of this disease, only 87 cases being reported in the literature in the United States to 1947, 2 practically all the investigative work has been done on the other forms of the disease. In 1947 Minden and Springer 2 reported a case of oculoglandular tularemia treated with streptomycin. In their case the temperature began to fall after twenty-four hours, reaching a normal level on the fourth day of therapy. A mild conjunctivitis and small palpable regional nodes were present after the fifth day. However, a low grade fever returned and was present for thirty days despite further treatment. Aureomycin, isolated by Duggar, 3 was first

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