Abstract
AbstractPurpose To compare ocular rigidity in patients with age‐related macular degeneration (AMD) and control subjects.Methods The ocular rigidity coefficient was measured in 32 patients with AMD (16 with neovascular and 16 with nonneovascular AMD) and 44 age‐matched control patients (control group) who underwent cataract surgery. The measurement procedure involved injection of microvolumes of a balanced salt solution (in steps of 4.5 microl) through the limbus in the anterior chamber, with continuous monitoring of intraocular pressure with a transducer, up to the limit of 30 mm Hg.Results There was no difference in age (p = 0.195), gender (p = 0.513) and axial length (p = 0.725) between the groups. Ocular rigidity coefficient was 0.0142 +/‐ 0.0077 μl‐1 in the AMD group and 0.0125 +/‐ 0.0049 μl‐1 in the control group (p = 0.255). In subgroup analysis, the average ocular rigidity was 0.0186 +/‐ 0.0078 μl‐1 in patients with neovascular AMD and 0.0104 +/‐ 0.0053 μl‐1 in patients with nonneovascular AMD. Ocular rigidity was higher in patients with neovascular AMD, compared to patients with nonneovascular AMD (p = 0.004) and controls (p=0.014).Conclusion Patients with neovascular AMD have increased ocular rigidity measurements compared with patients with nonneovascular AMD and control patients.
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