Abstract
Purpose: To investigate biomechanical properties of the cornea as measured using a Reichert ocular response analyzer (ORA) in a Taiwanese population. Methods: Basic demographic data were recorded for 1875 Taiwanese subjects. Corneal hysteresis (CH), corneal resistance factor (CRF), central corneal thickness (CCT), Goldmann-equivalent intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc) were measured with an ORA. Descriptive statistics and multiple regression analyses were used to assess and compare relevant factors of the CRF and CH. Results: In total, 1817 eyes were included in this study. The mean patient age was 21.4 ± 17.01 years. The mean (±SD) CH and CRF values were 10.6 ± 1.81 and 10.6 ± 1.99 mmHg, respectively. The mean CCT was 560.4 ± 38.53 μm. CH was correlated with IOPcc, CRF, and CCT. In the multiple linear-regression model, CH was associated with and affected by IOPcc, CRF, and CCT. In another multiple linear-regression model, CRF was associated with and affected by IOPcc, CH, and CCT. Conclusions: Measuring biomechanical properties by Reichert ORA, we found that CH and CRF values of a Taiwanese population were similar to those other Asian populations and other races. Our findings provided fundamental data of CH and CRF in a Taiwanese (ethic Chinese) and also Asian population.
Highlights
The cornea possesses both stiffness and viscoelasticity properties
There was no method to determine the corneal biomechanical properties until the use of Reichart ocular response analyzer (ORA) [2]. Both corneal hysteresis (CH) and corneal resistance factor (CRF) are derived using the Reichart ORA, and they were proposed as indicators of corneal biomechanical properties [3] [4]
Lim et al found that CH and CRF measurements did not vary with age, gender, or race and were not dependent on the refractive error or axial length [6]
Summary
The cornea possesses both stiffness and viscoelasticity properties. Hysteresis is a parameter to describe the biomechanical properties of the cornea [1]. There was no method to determine the corneal biomechanical properties until the use of Reichart ocular response analyzer (ORA) [2]. Both corneal hysteresis (CH) and corneal resistance factor (CRF) are derived using the Reichart ORA, and they were proposed as indicators of corneal biomechanical properties [3] [4]. The inward and outward applanations induced by the air puff are measured.
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