Abstract
AbstractPurpose To characterize the effect of intraocular pressure (IOP) on ocular pulsation parameters.Methods Fifty cataract patients (50 eyes) were enrolled. After cannulation of the anterior chamber, a computer‐controlled device for the intraoperative measurement and control of IOP was used to increase the IOP in a stepping procedure from 15 to 40 mm Hg. Recordings of IOP were acquired after each infusion step. Ocular rigidity was computed from the pressure‐volume data. Ocular pulse amplitude (OPA), pulse volume (PV), and pulsatile ocular blood flow (POBF) were measured from continuous IOP recordings.Results The average rigidity coefficient was 0.0224 μL‐1 (SD 0.0049). OPA increased by 91%, while PV and POBF decreased by 29% and 30%, respectively, when increasing the IOP from 15 to 40 mm Hg.Conclusion An increase in IOP is associated with an increased mechanical resistance of the ocular wall, an increase in OPA and decreased POBF.
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