Abstract

Introduction: High altitude has various effects on human beings. Altitude-related illnesses are a frequent cause of morbidity and occasional mortality in travelers to high altitudes throughout the world. Altitude has potential undesired ophthalmological effects too. Most of these problems are primarily preventable with an adequate level of information before and during travel. In this article, ophthalmological effects like altitude retinopathy and other ocular presentations of high altitude, likely to be encountered by mountaineers, are reviewed.Materials and methods: This is a hospital-based cross-sectional study from March 2016 to March 2017 done in Swacon International Hospital and Sleep Care Center, Kathmandu, Nepal. All the patients diagnosed as acute mountain sickness in the hospital during the study period were included. All the patients were evaluated by a physician and an ophthalmologist. All the findings were recorded in the proforma.Results: A total of 167 patients were admitted. Among them, 98 patients were diagnosed with acute mountain sickness; 20 patients had High altitude cerebral edema and 40 had High altitude pulmonary edema. Ocular findings, among patients who presented to our centre, were a high altitude retinopathy (28.48%) corneal abrasions (5.6%), snow blindness (8.86%), acetazolamide induced myopia (2.53%), conjunctivitis(8.22%), corneal ulcer (1.26%) and retinal detachment(0.63%).Conclusions: Mountaineers are at risk of developing high-altitude-related illnesses. Many other tissues in the eyes are also affected by high-altitude hypoxia, and effects can be observed on the conjunctiva, cornea, intraocular pressure, lens, uvea apart from the retina and the optic nerve.

Highlights

  • High altitude has various effects on human beings

  • Among them 98 patients were diagnosed of acute mountain sickness; 20 patients had High altitude cerebral edema and 40 had High altitude pulmonary edema

  • Among patients who presented to our centre, were high altitude retinopathy (28.48%) corneal abrasions (5.6%), snow blindness (8.86%), acetazolamide induced myopia (2.53%), conjunctivitis(8.22%), corneal ulcer (1.26%) and retinal detachment(0.63%)

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Summary

Introduction

High altitude has various effects on human beings. Altitude related illnesses are a frequent cause of morbidity and occasional mortality in travelers to high altitudes throughout the world. Altitude has potential undesired ophthalmological effects too. Most of these problems are primarily preventable with an adequate level of information before and during travel. Ophthalmological effects like altitude retinopathy and other ocular presentations of high altitude, likely to be encountered by mountaineers, are reviewed. The subdivisions are acute mountain sickness (AMS), high-altitude cerebral edema (HACE), high-altitude pulmonary edema (HAPE) and high-altitude retinopathy (HAR). High altitude cerebral edema and high altitude retinopathy are the conditions commonly seen in mountaineers and people who are introduced to high altitudes without proper acclimatization.[2] Acute mountain sickness, HACE and HAPE three life threatening conditions seen in persons who fail to get acclimatized to the hypobaric hypoxic condition. In diagnosing and analyzing these entities, the recognition of the signs and symptoms of each is indicated as follows

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