OCULAR MANIFESTATIONS IN GENODERMATOSES.

Abstract

PURPOSE: To evaluate the Ocular manifestations in patients with genodermatoses. METHODS: 49 cases in age group 16-60 years, with a diagnosis of genodermatoses were included in the study. All the patients underwent a complete ophthalmic examination, the ndings were noted. RESULTS: The most common condition noted was NF 1(23 cases) and NF 2 (18 cases). Other diseases seen were Dariers disease (1 case) Lamellar ichthyosis (7 cases) and Epidermal nevus syndrome (1 case). 10 cases out of 23(43.47%) having NF1 showed Lisch nodules, 13(56.52%) showed eyelid neurobromas and 1(4%) showed optic nerve glioma. In patients with NF2, 2 cases (11.11%) showed cataracts. Among patients with lamellar ichthyosis, 1 case (14.28%) had ectropion. In the patient with Epidermal nevus syndrome retinal pigment epithelium changes were seen. No ocular nding was seen in the patient with Dariers disease. Genodermatoses have si CONCLUSION: gnicant ocular ndings. These conditions are rare and hence it is essential to have a complete assessment of these patients with respect to ophthalmological manifestations for better diagnosis and earlier management.