Abstract
A 27-year old man presented with ocular symptoms and signs of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) who was also confirmed to have acute Lyme Disease (LD) by serology. The patient was treated timely for systemic LD and the APMPPE-like ocular findings regressed. Possible mechanism linking APMPPE and LD was discussed in conjunction with acute syphilitic posterior placoid choroiditis, another spirochete infection.
Highlights
Lyme Disease (LD) is a multisystem bacterial infection caused by the spirochete Borrelia burgdorferi [1]
A study of 18 cases of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) found that none had serum antibodies against Borrelia burgdorferi [8]
We describe a patient with confirmed LD who presented with ocular features resembling APMPPE
Summary
Lyme Disease (LD) is a multisystem bacterial infection caused by the spirochete Borrelia burgdorferi [1]. A variety of ocular manifestations in LD have been described, including multifocal choroiditis [2,3,4,5]. There have been several case reports, suggesting an association between acute posterior multifocal placoid pigment epitheliopathy (APMPPE) and LD [6,7]. A study of 18 cases of APMPPE found that none had serum antibodies against Borrelia burgdorferi [8]. We describe a patient with confirmed LD who presented with ocular features resembling APMPPE
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