Abstract
Objective The aim of this study was to investigate the relationship between high-order aberrations (HOAs) and monocular anisometropic amblyopia with or without strabismus. Patients and methods The medical records of 391 patients with monocular anisometropic amblyopia presenting to Sohag Refractive Center (Sohag, Egypt) were reviewed retrospectively in the period from May 2014 to December 2016. Ocular HOAs were measured using a Hartmann–Shack aberrometer and were used to compare the amblyopic eyes with the fellow eye on one hand and a control group of 380 individuals on the other hand. Results The study included 391 (190 men and 201 women) eyes of patients with anisometropic amblyopia. There was a significant difference between the amblyopic eyes and the control group regarding the total HOA, coma, and trefoil. In addition, hypermetropic amblyopes displayed higher HOA. Conclusion Anisometropic amblyopic eyes revealed higher ocular HOAs than fellow nonamblyopic eyes and the control group. Thus, HOAs should be incorporated in the treatment plan of amblyopia.
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