Abstract
Vaccination efforts as a mitigation strategy in the corona virus disease 2019 (COVID-19) pandemic are fully underway. A vital component of understanding the optimal clinical use of these vaccines is a thorough investigation of adverse events following vaccination. To date, some limited reports and reviews have discussed ocular adverse events following COVID-19 vaccination, but a systematic review detailing these reports with manifestations and clinical courses as well as proposed mechanisms has yet to be published. This comprehensive review one-year into vaccination efforts against COVID-19 is meant to furnish sound understanding for ophthalmologists and primary care physicians based on the existing body of clinical data. We discuss manifestations categorized into one of the following: eyelid, orbit, uveitis, retina, vascular, neuro-ophthalmology, ocular motility disorders, and other.
Highlights
Since the time that the first vaccines against the severe acute respiratory failure coronavirus 2 (SARS-CoV-2) and ensuing corona virus disease2019 (COVID-19) were approved for emergency authorization use by the Food and Drug Administration (FDA) in late 2020, an enormous amount of speculation has surrounded the discourse around vaccination and COVID-19 [1–4]
Regardless of the mechanism, we propose that ophthalmologists consider examining patients with corneal grafts prior to vaccination against COVID-19 in order to evaluate underlying inflammatory processes which may be further exacerbated by the introduction of a profound immunogenic stimulus such as a COVID-19 vaccine
Since the introduction of COVID-19 vaccinations, numerous reports have commented on adverse ocular events following vaccination
Summary
Since the time that the first vaccines against the severe acute respiratory failure coronavirus 2 (SARS-CoV-2) and ensuing corona virus disease2019 (COVID-19) were approved for emergency authorization use by the Food and Drug Administration (FDA) in late 2020, an enormous amount of speculation has surrounded the discourse around vaccination and COVID-19 [1–4]. It remains the consensus opinion in clinical practice—and the opinion of the authors—that vaccination and subsequent booster administration against COVID-19 is a vital epidemiologic factor in mitigating the devastating effects of the COVID-19 pandemic. We seek to provide a rigorous description of these findings based on a comprehensive review and statistical analysis of the literature
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
