Abstract

SummaryFast and high‐resolution cross sectional imaging of the cornea by OCT proves essential in corneal graft: (i) during Eye Banking: non‐contact safe and accurate thickness measurements are available to guide pre‐cutting of DSAEK and control cut regularity; (ii) diagnosis and follow‐up of corneal diseases undoubtedly benefit from OCT that can help establishing indication for graft; (iii) after endothelial keratoplasty (EK), OCT shows graft position and adherence to the recipient bed and endothelial function through corneal thickness; (iv) after all grafts, OCT provides topography, thickness (useful during rejection and late endothelial failure), and images of donor/host interface and irido‐corneal angle; (v) The place of Iintra operative OCT expands rapidly, allowing an easy control of EK orientation, improving the safety of DALK or femtosecond laser‐assisted keratoplasty, and allowing the development of new techniques like intrastromal lamellar graft. Exciting perspectives will be illustrated with 2 examples: (i) an Optical Coherence Microscope that combines the large field of OCT and the cellular resolution of confocal microscopy; (ii) the monitoring of thickness during storage in a innovative bioreactor that restores the intra ocular pressure.

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