Abstract

SummaryThe clinically significant macular oedema, related to the macular microcirculation abnormal permeability, ischemic changes or aneurysmal changes, were identified during the evolution of the most common retinal ischemic micro‐angiopathies.Intravitreal anti‐VEGF or steroids demonstrated their efficacy to reverse the macular blood retinal barrier changes, resolving the characteristic oedematous macular changes leading to the observed clinically significant functional improvement.The confrontation of the OCT‐angiography monitoring of the superficial and deep capillaries plexus changes to the fluoresceine angiography observed persistent leaking capillaries segment or micro‐aneurysms, allows the applications precise focal laser treatment.Intravitreal anti‐VEGF associated to focal laser treatment results to superior functional results than intravitreal anti‐VEGF alone in late onset treated BRVO cases.

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