Abstract
A 10-year-old Lebanese boy developed systemic lupus erythematosus 3 months after the administration of ethosuccimide (Zarontin), 500 to 750 mg. per day. Prednisone, 60 mg. per day, was administered orally for-6 months. The child's clinical manifestations (fever, general well-being, rash, lymphadenopathy, hepatic and splenic enlargement) disappeared within 3 weeks, and the lupus erythematosus preparation became negative within 3 months after the discontinuation of the drug. Seventeen months after cessation of ethosuccimide therapy, and 11 months after discontinuing administration of prednisone, the child remains in good health and has no clinical or laboratory evidence of activity of disease.
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