Occurrence of multiple combinations of G and P types of group A bovine and human rotaviruses in Uttarakhand and Nagaland states, India

Abstract

The present study describes the distribution of RV in bovine and human population from Uttarakhand and North eastern region of India. Group A rotavirus (RVA) was detected in 17.33% and 15.68% diarrhoeic cases from bovine and humans, respectively. All bovine RVA isolates were long electropherotypes whereas, in human RVA isolates both long and short electropherotypes were detected. Genotyping by multiplex RT-PCR revealed presence of G3 and G10 genotypes in bovine and G1 and G3 in humans. Among P types, P[1] and P[11] in bovine and P[4] and P[8] in human were detected. The G and P type combinations present were G3P[11], G10P[1], G3P[1]P[11], G10P[1]P[11], G3G10P[1]P[11], G3G6G10P[1] and G3G6G10P[11] in bovine, while G1P[4], G3P[8] and G1G3P[8] in human samples.