OCCURRENCE OF d-AMINO ACIDS IN SOME NATURAL MATERIALS

Carl M Stevens,Philip E Halpern,Richard P Gigger

doi:10.1016/s0021-9258(18)56019-1

Abstract

OCCURRENCE OF d-AMINO ACIDS IN SOME NATURAL MATERIALS

Highlights

In the case of B. brevis, the total quantity of n-amino acids found in acid hydrolysates, while high, was not nearly so large as that reported by Konikova and Dobbert [5]
The indications that n-aspartic acid is an important component of acid hydrolysates of B. brevis cells and that it is excreted in the urine after feeding of unhydrolyzed material are of particular interest because it is apparently the first instance of the finding of n-aspartic acid in this organism
A study has been made of the occurrence of n-amino acids in acid hydrolysates of cells of Lactobacillus arabinosus, Bacillus brevis, Bacillus subt&s, Torulopsis utilis, and mycelia of Penicillium chrysogenum

Summary

ACID IN NATURAL

MATERIALS od before hydrolysis of the materials. Total a-amino N was determined after hydrolysis by the method of Pope and Stevens [8]. It will be noted that the hydrolysates of P. chrysogenum mycelia contained insignificant amounts of n-amino acids as estimated by this technique. Hydrolysates of L. arabinosus and B. brevis contain relatively large amounts, in the latter case over 10 per cent of the total amino acids. There is considerable evidence in the literature [19, 20] that a number of D-amino acids are largely excreted in the urine when fed to experimental animals. This fact has been utilized by Kijgl [4] in attempting to establish the occurrence of n-glutamic acid in malignant tissue.

Total arhino N per cent

After hydrolysis

Findings

DISCUSSION

SUMMARY