Abstract
In 42 consecutive adult patients with benign gastric ulcers, endoscopic biopsy specimens were examined histologically for infiltration with Candida albicans before the patients entered a double-blind trial of either cimetidine or placebo. Fifteen cases of candidal infiltration were found, giving an overall incidence of 36%. Repeated endoscopy after 6 wk showed complete ulcer healing in 9 of 15 patients with Candida-infiltrated ulcers, compared with 20 of 27 patients with no infiltration. It is concluded that the occurrence of Candida in benign gastric ulcers has no influence on the healing process.
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