Abstract
Normal skin color is an admixture of the following chromophores: red (oxyhemoglobin); blue (deoxygen-ated hemoglobin); yellow-orange (carotene); and brown (melanin), the major component (Mosher et al. 1993). Environmental exposures that disturb these color factors may result in various pigmentary changes. Disorders of occupational pigmentation are classified as: (1) the presence or absence of melanin in melanosomes responsible for epidermal pigmentation; (2) the presence of melanin in dermal melanophages, responsible for dermal pigmentation; (3) deposits of metallic substances or pigmented particles (tattooing) in the skin; (4) chemical discoloration or staining of the skin from external contact with a dye or deposition of chemicals or dyes after ingestion, inhalation or percutaneous absorption.
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