Abstract
The causes of occupational nephropathy can be production factors of both chemical and physical nature. Thus, occupational toxic nephropathy can be caused by heavy metals and their compounds (mercury, lead, cadmium, lithium, bismuth, gold, etc.), arsenic compounds, organic solvents (carbon tetrachloride, dichloroethane, ethylene glycol, etc.), various pesticides (organomercury, organochlorine and phosphorus compounds), beta-naphthol, etc. Occupational nephropathies are caused by such physical factors as radiation damage, exposure to high and low temperatures of the industrial environment, hypothermia. In addition, malignant neoplasms of the bladder (bladder cancer) take a significant place among the occupational lesions of the kidneys and urinary tract. Chemicals with proven carcinogenic effects include aromatic amino compounds (benzidine, dianisidine, 2‑naphthylamine) used in the manufacture of dyes.
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