Abstract
Today breast cancer is the most common cancer type in women, in both developed and developing countries. However, occult breast cancer is a highly rare type in all breast cancers. For the first time in history to know, Halsted defined the term “occult breast cancer” with 2 cases of his’ in the journal, Annals of Surgery. We have 2 similar cases who were 52 and 61-years-old patients and presented our clinic with left axillary swelling and pain. On physical examination and with imaging techniques there wasn’t any primary lesion found. Examination of lymph nodes’ biopsy material was compatible with breast cancer metastasis for both of the patients and they were diagnosed with occult breast cancer. They underwent a modified radical mastectomy surgery and axillary curettage. Histopathologic examination of the excised breast material revealed T1 invasive breast cancer.International Journal of Human and Health Sciences Vol. 02 No. 04 October’18. Page : 239-243
Highlights
Smith Surgery Papyrus is the first known document to cite breast cancer B.C. 3000-2500
For the first time Radical Mastectomy surgery method has been used by Halsted in 1894.1 Today breast cancer is the most common cancer type in women, in both developed and developing countries
Occult breast cancer, is a type of breast cancer which doesn’t have any manifestations in physical exam or in any imaging study and shows itself only by axillary lymphadenopathy. It is described by William Halsted with two presented cases in the journal Annals of Surgery, 1907.3 Incidence of this rare cancer type is less than 0,34-0,88% amongst all breast cancers.[4,5,6,7]
Summary
Smith Surgery Papyrus is the first known document to cite breast cancer B.C. 3000-2500. Since imaging studies showed no sign of a primary focus, left axillary lymph node dissection was performed and material was analyzed pathologically and dyed ER, PR, Ki-67, mammaglobin and CA-125 positive; CERB-B2 negative. Case 2: Sixty one-year-old women with positive family history of breast cancer, presented to our hospital with complain of left axillary mass. She reported that her daughters were diagnosed as breast cancer. Evalu- left breast and 39x21mm, solid, pathological ation of the dissected material showed estrogen lymph nodes without fatty hilus were observed receptor, progesterone receptor, E-cadherin with in left axilla. There was a focal nuclear staining and membranous expression with E-cadherin According to these findings, there was carcinoma metastases and extracapsular invasion in three of the eleven lymph nodes.
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