Abstract

IntroductionATG16L1 has been implicated in the susceptibility to Crohn's disease (CD), notably the T300A (rs2241880, exon 9). In ATG16L1-deficient and hypomorphic mice, autophagy, Paneth-cell homeostasis and IL-1b secretion were dependent...

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.