Obstructive sleep apnoea, obesity hypoventilation, trisomy 21 and intellectual disability in a 19 year old female – 2016 – Royal Melbourne Hospital

Abstract

Introduction: Obesity Hypoventilation Syndrome (OHS) is estimated to occur between 10% and 20% of patients with obstructive sleep apnoea (OSA) (Mokhlesi et al., 2008; La Aban and Chailleux, 2005). The most common symptoms and signs are due to the co-existing OSA (Mokhlesi, 2007), and include excessive daytime sleepiness, loud snoring, choking during sleep, resuscitative snorting fatigue, hypersomnolence, impaired concentration and memory, a small oropharynx, and a thick neck (Nowbar et al., 2004). Non-invasive ventilation is an effective form of treatment in patients with obesity hypoventilation syndrome (OHS), and have obstructive sleep apnoea (OSA) (Salord et al., 2013).