Abstract
The closing volume of the small airways was measured using the argon bolus technique by mass spectrography in 20 males 3 to 5 months after acute myocardial infarction. No patient exhibited signs of a manifest heart failure or of a simultaneous pulmonary disease. The closing volume expressed in percent of vital capacity exceeded in only 2 patients the limits of + 2 SD of our own normal values. A slight arterial hypoxemia was established in 45% of patients but its correlation to closing volume was not significant. Also, no correlation was found to the alveoloarterial oxygen pressure gradient, vital capacity, or expiratory forced volume. The hemodynamic changes in the lesser circulation were examined in all patients with floating catheter. The closing volume showed no correlation to the pulmonary artery diastolic pressure (regarded as an index of left ventricular filling pressure), nor to the pulmonary mean pressure both at rest and during effort.
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