Abstract
Purpose: The reason for gastrointestinal system (GIS) motility problems in premature infants is multifactorial and intestinal immaturity is the most important contributing factor. To investigate the effect of epidural (EA) or general anesthesia (GA) on GIS function and early neonatal morbidity in preterm infants delivered by cesarean section (CS).Materials and Methods: This study was conducted in a single neonatal intensive care unit (NICU) between October 2011 and April 2015. Preterms ≤32 weeks and ≤1500g who were delivered by CS were enrolled in this study. Mode of anesthesia, demographic, clinical characteristics, first meconium passage time, meconium obstruction, use of drug for dysmotility and other preterm morbidities were evaluated. Results: Three hundred and sixty four preterm infants were enrolled during the study period. Use of drug for dysmotility, time to first meconium passage, and meconium obstruction rate, were significantly higher in the GA group. Conclusion: This was the first study in the literature that investigated the role of anesthesia methods, effect on preterm infant GIS motility. Anesthesia modalities during delivery may have an effect on GIS function in preterm infants.
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