Obstetrics mortality and associated factors in intensive care unit of Addis Ababa public hospital in, 2020/21: A hospital based case control study

Abstract

BackgroundIn low-income nations like Ethiopia, the rate of obstetric death in intensive care units is significant. The indications of admission are Preeclampsia/Eclampsia, postpartum hemorrhage, and puerperal sepsis but, patient outcomes subsequent to intensive care unit admission are sparse. The aim of this study is to assess factors associated with obstetrics mortality in Intensive Care unit. MethodsA hospital based unmatched case control study was conducted on obstetrics patients admitted to Addis Ababa Public hospital's intensive care unit from October 2018 to November 2020. Multivariable logistic regression analysis was done; Odds Ratio and Confidence Interval (OR and 95% CI) were computed using SPSS version 26. P value < 0.05 was taken as statistically significant. ResultObstetrics mortality in intensive care unit was high and accounts 27% from the total intensive care unit admission. Severe pre-eclampsia AOR: 6.33; 95% CI: 2.25–17.79, puerperal sepsis AOR: 4.51; 95% CI: 1.68–12.15, age ≥35 years AOR: 4.09; 95% CI: 1.42–11.77, absence of antenatal care: AOR: 3.74; 95% CI: 1.03–13.5, maternal coexisting diseases AOR: 5.2; 95% CI: 2.22–12.16, and severely decrease of consciousness at admission AOR: 3.78; 95% CI: 1.21–11.79 were significantly associated with obstetrics mortality in Addis Ababa Public Hospitals intensive care unit. Conclusionand Recommendation: Maternal age ≥35 years, loss of antenatal care, puerperal sepsis, severe pre-eclampsia, pre-existing medical comorbidities and severe decrease level of consciousness during ICU admission were the most significant factors associated with obstetrics mortality. It is recommended that all pregnant women should have antenatal care so that preeclampsia and maternal comorbidities will be early diagnosed and treated.