Obstetrical Acute Kidney Injury: Epidemiology and Clinical Aspects in Teaching Hospital of Ignace Deen, Conakry Guinea

Ibrahima Koussy Bah,Abdouramane Diallo,Mamadou Yacine Bah,Alpha Boubacar Bah,Mamadou Saliou Baldé,Amadou Yaya Diallo,Moussa Traore,Telly Sy Diallo,Alpha Oumar Bah,Fousseny Diakite

doi:10.4236/crcm.2020.91006

Abstract

Introduction: In Guinea, data on the acute kidney injury (AKI) of women in the obstetrical context is still limited. This study attempted to determine the prevalence and the clinical signs of obstetric AKI in Guinea. Patients and methods: The study population consisted of pregnant or postpartum women with AKI, whom we treated in this institute from August 2018 to January 2019. All had normal anterior renal function with serum creatinine clearance ≥ 120 μmol/L, and then suffered AKI. Patients characteristics were examined; maternal age, gestational weeks, AKI characteristics. Results: Of 2438 pregnant women admitted during the study period, 56 showed AKI. Antepartum and postpartum AKI accounted for approximately 80% and 17%, respectively. Regarding the maternal age, <25 years of age accounted for 54% (range: 17 - 40). Multiple gestations accounted for 34 (60.71%) of which functional AKI, organic AKI, and obstructive AKI accounted for 28/34, 2/34, and 4/34, respectively. Regarding the clinical manifestations, abdominal pain, tinnitus, visual disturbances, edema of the lower limb, and facial swelling accounted for 79%, 75%, 7%, 57%, and 54%, respectively. Conclusion: We here demonstrated peripartum AKI in Guinea, which findings may provide fundamental data to establish some strategy against this condition in this region.

Highlights

In Guinea, data on the acute kidney injury (AKI) of women in the obstetrical context is still limited
Abdominal pain, tinnitus, visual disturbances, edema of the lower limb, and facial swelling accounted for 79%, 75%, 7%, 57%, and 54%, respectively
The objective of our work was to determine the prevalence of obstetric AKI and to describe the clinical manifestations observed in parturients

Summary

Introduction

In Guinea, data on the acute kidney injury (AKI) of women in the obstetrical context is still limited. This study attempted to determine the prevalence and the clinical signs of obstetric AKI in Guinea. Patients and methods: The study population consisted of pregnant or postpartum women with AKI, whom we treated in this institute from August 2018 to January 2019. Multiple gestations accounted for 34 (60.71%) of which functional AKI, organic AKI, and obstructive AKI accounted for 28/34, 2/34, and 4/34, respectively. It is a serious and formidable complication in obstetric settings. Pregnancy-related ARI can be induced by the same causes as in the general population (functional, parenchymal, obstructive and septic causes) [3] but is more frequently related to specific pathologies of pregnancy with a different chronological distribution function of the term of pregnancy [4]

Objectives

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Results

Conclusion