Abstract
Objective To investigate the current situation of depression/anxiety in gravidas and to analyze the related obstetric factors. Methods A questionnaire survey was conducted among 6 923 gravidas who registered for their first prenatal examination at Obstetrics and Gynecology Hospital of Fudan University from September 2015 to September 2016. Self-Rating Depression Scale (SDS) and Self-Rating Anxiety Scale (SAS) were completed during the survey and general obstetric conditions and medical history were reviewed. Related obstetric factors were statistically analyzed by Chi-square test and logistic regression. Results In this study, the positive rates of depression and anxiety screening were 23.15% (1 603/6 923) and 9.56% (659/6 893), respectively. Univariate analysis showed that maternal depression was associated with maternal age, gravidity, parity and history of adverse pregnancies (all P<0.05), while anxiety was related to maternal age, gravidity and history of adverse pregnancies (all P<0.05). Multivariate analysis showed that younger gravidas (<25 years old) had higher risks of depression and anxiety than those aged between 25 and 35 (OR=2.945, 95%CI: 2.266-3.829; OR=1.959, 95%CI: 1.381-2.780; both P<0.05). Compared to primiparas with a history of conception, the first-time pregnant women had lower risks of depression and anxiety (OR=0.732, 95%CI: 0.630-0.851; OR=0.630, 95%CI: 0.512-0.775; both P<0.05), and the risk of anxiety in multiparas was also decreased (OR=0.748, 95%CI: 0.561-0.996, P<0.05). In addition, gravidas with previous adverse pregnant outcome showed higher risks of depression and anxiety (OR=1.549, 95%CI: 1.123-2.137; OR=1.712, 95%CI: 1.138-2.577; both P<0.05). Conclusions The positive rates of depression and anxiety are high in gravidas, especially younger or primiparas with a history of conception and those with history of adverse pregnancies. Clinicians should pay attention to any obstetric factors related to maternal depression and anxiety. Key words: Pregnant women; Depression; Anxiety; Psychiatric status rating scales; Age factors; Pregnancy outcome
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