Abstract

Abstract The phenomenon of spontaneous left ventricular ejection fraction (LVEF) recovery is becoming increasingly apparent and is an area of new understanding and study. This article highlights the emerging appreciation of LVEF recovery and how the process of reverse cardiac remodeling leads to a group of patients who experience improvements in LVEF and clinical outcomes, yet likely harbor continued residual risk. We specifically address (1) differences in LVEF recovery versus myocardial recovery and remission, (2) predictors of LVEF recovery, (3) clinical course after LVEF recovery, and (4) current knowledge gaps in the management of this evolving phenotype and future directions.

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