Abstract
The impact of obsessive-compulsive symptoms on functioning in schizophrenia is still debated. This study investigated the relationship between OC symptoms and functioning along a severity gradient of obsessive-compulsive dimension. Sixty patients affected by schizophrenia completed the SCID-IV, the Positive and Negative Syndrome Scale, the Yale-Brown Obsessive-Compulsive Scale and the Social and Occupational Functioning Assessment Scale. The relationship between functioning and obsessive-compulsive dimension was described by a reverse U-shaped curve; functioning was positively related to the presence of mild obsessive-compulsive symptoms and inversely related to moderate and severe symptoms, after controlling for the severity of positive, negative, disorganization and general psychopathological symptoms. The role of obsessive-compulsive symptoms on social functioning in schizophrenia occurs along a severity continuum with a gradual transition from a positive correlation (from absent to mild symptoms) to an inverse correlation (for symptoms ranging from moderate to severe) and independently from schizophrenia symptom dimensions.
Highlights
The rate of co-morbid obsessive–compulsive disorder (OCD) with both bipolar disorder and schizophrenia is high [1]
A 5-year follow-up study [10] has suggested that the severity of OC features might differentially impact social functioning in schizophrenia, with sub-threshold symptoms showing an improving effect and full-blown OCD a worsening one: Among patients with schizophrenia, those with obsessive–compulsive symptoms (OCS) showed a better social functioning than both patients without OCS and with OCD
Social and Occupational Functioning Assessment Scale (SOFAS) and Positive and Negative Syndrome Scale (PANSS) scores did not vary as a function of gender, while Yale-Brown Obsessive–Compulsive Scale (YBOCS) total score was Patients (n = 60)
Summary
The rate of co-morbid obsessive–compulsive disorder (OCD) with both bipolar disorder and schizophrenia is high [1]. While co-morbid obsessive–compulsive symptoms (OCS) have been associated with poorer functioning as compared to “pure” bipolar disorder, with respect to schizophrenia, data seem more contradictory [2, 3]. The present study was aimed at evaluating whether, in patients with schizophrenia, the relationship between OC dimension and functioning varies along a severity continuum, with a qualitatively different correlation moving from mild to severe OC symptoms. Her own mind were considered as obsessions. A trained psychiatrist interviewed patients after the resolution of the acute phase of illness in order to guarantee an adequate cooperation to the assessment
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